BDBM50240612 CHEMBL306946::GNF-PF-2691::Indolo[2,1-b]quinazoline-6,12-dione::TCMDC-125859::TRYPTANTHRIN::US10669273, Compound 5a
SMILES O=C1c2ccccc2-n2c1nc1ccccc1c2=O
InChI Key InChIKey=VQQVWGVXDIPORV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50240612
Affinity DataKi: 4.81E+3nMAssay Description:Mixed competitive inhibition of human recombinant IDO1 using L-tryptophan as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as kynurenine release after 5 hrs by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.99E+5nMAssay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
Affinity DataIC50: 7.15E+3nMAssay Description:Mixed competitive inhibition of human recombinant IDO1 using L-tryptophan as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair